Botox: Commercially Available Varieties

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CJ Conlon, MD
Plastic Surgeon
September 2025

Understanding Different Types of Botox: A Guide to Botulinum Toxins

When most people hear "Botox," they think of a single treatment. However, Botox is actually a common term that encompasses an entire class of medications known as botulinum toxins. While all these treatments achieve similar cosmetic and therapeutic results, each formulation has unique properties that may make one more suitable for your specific needs than another.

The Original: Botox (OnaBotulinumtoxinA)

The original Botox formulation remains one of the most widely used botulinum toxins in plastic surgery. As the first FDA-approved treatment in this category, it has the longest track record and extensive research backing its safety and effectiveness.

Key considerations: It's important to note that with any botulinum toxin, including original Botox, some patients may develop resistance over time due to side-chains inherent to the toxin.

Dysport (AboBotulinumtoxinA)

Dysport offers some distinct advantages that make it a popular choice among both surgeons and patients:

  • Faster onset: Many patients notice results more quickly compared to other formulations
  • Shorter duration: While this might seem like a disadvantage, some patients prefer more frequent touch-ups for better control over their results

Xeomin (IncoBotulinumtoxinA)

Xeomin stands out for its unique formulation and storage requirements:

  • No refrigeration needed: This makes shipping and storage more convenient
  • Purified formula: Contains fewer accessory proteins
  • Anecdotal reports: Some practitioners note it may require slightly higher doses to achieve similar results

Jeuveau (PraBotulinumtoxinA)

Often called "Newtox," Jeuveau is specifically designed for aesthetic use:

  • Quick onset: Similar to Dysport, many patients report seeing results relatively quickly
  • Aesthetic focus: Developed specifically for cosmetic applications

Letybo (LetiBotulinumtoxinA)

The newest addition to the U.S. market, Letybo brings international experience to American practices:

  • International background: Successfully used in Korea before arriving in the U.S.
  • FDA status: Currently operates under a temporary FDA waiver
  • Practitioner feedback: Some anecdotal reports suggest it may require adjustment in dosing

Choosing the Right Treatment for You

All botulinum toxin formulations accomplish similar effects in reducing wrinkles and treating various medical conditions. The choice between them often comes down to:

  • Your surgeon's experience and preferences
  • Your individual response to different formulations
  • Specific treatment goals and timeline preferences
  • Any previous experiences with botulinum toxins

The Bottom Line

While the marketing names and specific properties may differ, all FDA-approved botulinum toxins are safe and effective when administered by qualified practitioners. The "best" option is the one that works most effectively for your unique situation and goals.

Consultation is Key: During your consultation, discuss your preferences, timeline, and any previous experiences with botulinum toxins. Your surgeon can recommend the most appropriate formulation based on their expertise and your individual needs.

This information is for educational purposes only and should not replace professional medical advice. Always consult with a qualified plastic surgeon to determine the best treatment options for your specific needs.

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CJ Conlon, MD
Plastic Surgeon
September 23, 2025

Understanding Different Types of Botox: A Guide to Botulinum Toxins

When most people hear "Botox," they think of a single treatment. However, Botox is actually a common term that encompasses an entire class of medications known as botulinum toxins. While all these treatments achieve similar cosmetic and therapeutic results, each formulation has unique properties that may make one more suitable for your specific needs than another.

The Original: Botox (OnaBotulinumtoxinA)

The original Botox formulation remains one of the most widely used botulinum toxins in plastic surgery. As the first FDA-approved treatment in this category, it has the longest track record and extensive research backing its safety and effectiveness.

Key considerations: It's important to note that with any botulinum toxin, including original Botox, some patients may develop resistance over time due to side-chains inherent to the toxin.

Dysport (AboBotulinumtoxinA)

Dysport offers some distinct advantages that make it a popular choice among both surgeons and patients:

  • Faster onset: Many patients notice results more quickly compared to other formulations
  • Shorter duration: While this might seem like a disadvantage, some patients prefer more frequent touch-ups for better control over their results

Xeomin (IncoBotulinumtoxinA)

Xeomin stands out for its unique formulation and storage requirements:

  • No refrigeration needed: This makes shipping and storage more convenient
  • Purified formula: Contains fewer accessory proteins
  • Anecdotal reports: Some practitioners note it may require slightly higher doses to achieve similar results

Jeuveau (PraBotulinumtoxinA)

Often called "Newtox," Jeuveau is specifically designed for aesthetic use:

  • Quick onset: Similar to Dysport, many patients report seeing results relatively quickly
  • Aesthetic focus: Developed specifically for cosmetic applications

Letybo (LetiBotulinumtoxinA)

The newest addition to the U.S. market, Letybo brings international experience to American practices:

  • International background: Successfully used in Korea before arriving in the U.S.
  • FDA status: Currently operates under a temporary FDA waiver
  • Practitioner feedback: Some anecdotal reports suggest it may require adjustment in dosing

Choosing the Right Treatment for You

All botulinum toxin formulations accomplish similar effects in reducing wrinkles and treating various medical conditions. The choice between them often comes down to:

  • Your surgeon's experience and preferences
  • Your individual response to different formulations
  • Specific treatment goals and timeline preferences
  • Any previous experiences with botulinum toxins

The Bottom Line

While the marketing names and specific properties may differ, all FDA-approved botulinum toxins are safe and effective when administered by qualified practitioners. The "best" option is the one that works most effectively for your unique situation and goals.

Consultation is Key: During your consultation, discuss your preferences, timeline, and any previous experiences with botulinum toxins. Your surgeon can recommend the most appropriate formulation based on their expertise and your individual needs.

This information is for educational purposes only and should not replace professional medical advice. Always consult with a qualified plastic surgeon to determine the best treatment options for your specific needs.

Copy link to post

https://www.conlonplasticsurgery.com/post/botox-commercially-available-varieties